Leveraging the Beckman Coulter Avanti JXN-26 with JLA-16.250 and JLA-8.1000 Rotors
Service AI
High-performance separations in modern bioprocessing demand both high g-forces and the ability to handle substantial sample volumes. The Beckman Coulter Avanti JXN-26 high-speed centrifuge, paired with the J-Lite JLA-16.250 and J-Lite JLA-8.1000 fixed-angle rotors, offers a documented and versatile combination that supports medium- and large-volume workflows on a single platform.
Avanti JXN-26: High-Speed Refrigerated Workhorse
The Avanti JXN-26 is a refrigerated, high-performance centrifuge designed to generate the centrifugal forces required for a wide range of laboratory applications when used with approved Beckman Coulter rotors. Documented applications include:
Routine sample processing: pelleting, extractions, purifications, concentrations, phase separations, and spin column/spin filter centrifugations
Rapid sedimentation of protein precipitates, large particles, and cell debris
Preparation of subcellular organelles (for example, mitochondria, nuclei, chloroplasts, crude microsomes)
Separation of blood cells and cellular components
Pelleting of prokaryotic and eukaryotic cells
Gradient separations (e.g., Ficoll-Hypaque, Percoll)
Nucleic acid precipitation, virus isolation, and bacteriophage isolation
The JXN-26 combines a high-torque, brushless drive with a refrigerated chamber and programmable acceleration/deceleration, making it suitable for both routine and demanding preparative workflows.
Medium-Volume, High-g Processing with the JLA-16.250 Rotor
The J-Lite JLA-16.250 rotor is a fixed-angle, 6-place aluminum rotor designed for Avanti J-series instruments, including the Avanti JXN-26.
Key specifications:
Fixed-angle rotor, 25°, 6 places
Maximum radius (r_max): 134 mm
Maximum speed on Avanti JXN-26: 16,000 rpm
Maximum RCF on Avanti JXN-26: 38,420 × g
Capacity: 6 × 250 mL (total 1.5 L)
This rotor is documented for general-purpose, large-volume, multitube work and is referenced in protein purification workflows, particularly in steps where protein must be efficiently separated from non-protein contaminants and cellular debris. Its combination of medium volume and high g-force makes it well suited for:
Clarification of lysates after cell disruption
Sedimentation of protein precipitates at high g
Medium-scale pelleting of cells and organelles
Multitube processing where 50–250 mL tube formats are preferred
For labs that routinely cycle between protein purification steps and other preparative tasks, the JLA-16.250 on the JXN-26 provides a strong balance of capacity, speed, and turnaround time.
High-Volume Harvesting with the JLA-8.1000 Rotor
When workflows move into truly large-volume territory, the J-Lite JLA-8.1000 rotor extends the capacity of the Avanti JXN-26 to the liter scale.
Key specifications:
Fixed-angle, 6-place J-Lite aluminum rotor
Capacity: 6 × 1,000 mL bottles (total 6 L)
Maximum speed: 8,000 rpm
Maximum RCF: 15,970 × g
This rotor is documented for:
General-purpose, large-volume processing
Harvest and pelleting of bacteria
Pelleting of cell organelles, viruses, and precipitates
Protein concentration from large volumes
On the JXN-26, this rotor allows efficient processing of up to six liters per run at high relative centrifugal force. That makes it particularly useful for upstream and mid-stream steps such as:
Bulk harvest of microbial or cell culture biomass
Concentration of secreted proteins or virus particles from large culture volumes
Large-batch clarification prior to finer purification steps with smaller-volume rotors
The lightweight J-Lite construction helps keep handling manageable despite the high capacity.
A Unified Platform for Medium- and Large-Volume Bioprocessing
Using the Avanti JXN-26 with both the JLA-16.250 and JLA-8.1000 rotors gives a lab a documented, vendor-supported way to cover a broad range of bioprocessing and molecular biology tasks:
The JLA-16.250 supports medium-volume, high-g workflows such as protein purification, clarification, and multitube processing up to 1.5 L per run.
The JLA-8.1000 extends the system to high-volume harvest and concentration, handling up to 6 L per run for biomass, organelles, viruses, and protein concentrates.
The JXN-26 platform itself is documented for routine sample processing, organelle preparation, cell pelleting, gradient separations, nucleic acid work, virus and bacteriophage isolation, and related applications when used with appropriate rotors and accessories.
For research groups that need both capacity and flexibility on an established high-speed platform, this combination provides a clear, technically defined path from large-volume harvest to high-g clarification and purification—without changing instruments.
How Service AI Adds Value: Professional Crating and Onsite Installation
Beyond sourcing reliable instrumentation, Service AI helps laboratories put these systems into service smoothly and safely:
Professional crating and shipment
The Avanti JXN-26 centrifuge from Service AI is professionally packed in robust, purpose-built wooden shipping crates designed to protect the instrument, rotors, and accessories during transport. Attention to bracing, cushioning, and weight distribution helps minimize the risk of transit damage and keeps the system aligned and ready for installation on arrival.Onsite installation by trained personnel
Service AI can arrange onsite installation by trained technical personnel. This includes positioning and leveling the centrifuge, verifying utilities and clearances (site preparation), assisting with rotor setup, and walking through basic operation and safety checks. Proper installation helps ensure that the instrument performs to specification and gives users confidence from day one.
By combining this refurbished, documented Beckman Coulter centrifuge with professional crating and onsite installation support, Service AI aims to provide laboratories with high-performance centrifugation solutions that are not only cost-effective but also ready to integrate into demanding research workflows with minimal downtime.
